MICR/MBMB 460

Bacterial and Viral Genetics

Fall, 2011
Department of Microbiology, Southern Illiniois University

Syllabus and Schedule
Instructor: Dr. Kelly Bender
Office: 106 Life Science II
Office Hours: 9:00 am - 10:00 MWF or by appointment
Office Phone: 453-2868
E-mail:


Text: Molecular Genetics of Bacteria, 3rd Edition, Snyder and Champness, 2007
Course Objectives: To understand the genetic processes of bacteria and viruses and to examine the molecular mechanisms that control these processes.

Grading: Hourly exams 200 (Best two exam scores out of three)
Final exam 200 (Cumulative)
Pop quizzes: 20 points (five quizzes worth 5 points each; lowest score dropped)
Total 420 points

There will be NO make-up exams or quizzes. If you miss an exam or a quiz, it will be considered your drop exam or quiz. Grading will be based solely on exam scores on a typical 10-percentage point grading scale.
90-100% (420-378 pts) = A; 80-89% (377-336 pts)= B; 70-79% (335-294 pts) = C; 60-69% (293-252 pts) = D; <59% (≤ 251 pts) = F.


SEE BLACKBOARD TO DOWNLOAD PARTIAL LECTURE SLIDES:

https://mycourses.siu.edu/webct/entryPageIns.dowebct

Lecture

Date

Topic

Chapter

1

8/22

DNA Structure/DNA Replication

1

2

8/24

Chromosome Replication/Cell Division

1

3

8/26

DNA Repair

11

4

8/29

Transcription

2

5

8/31

Translation

2

6

9/02

Translation and Proteins

2

-

9/05

Labor Day

-

7

9/07

Nomenclature, Inheritance, Mutations, Phenotypes

3

8

9/09

Plasmids

4

9

9/12

Conjugation

5

10

9/14

Conjugation

5

11

9/16

Transformation and Horizontal Transfer of Genes

6/ref list

-

9/19

First Hourly Exam (Lectures 1-11)

-

12

9/21

Transduction

7/8/3

13

9/23

T4 Phage Genetics

7/3

14

9/26

Lambda Lytic Life Cycle

7

15

9/28

Lambda Lysogenic Life Cycle

8

16

09/30

Lambda Control Mechanisms

8

17

10/03
Lambda Control Mechanisms
8

18

10/05

Phage Toxins

ref list

19

10/07

Phage Toxins

ref list

-

10/10

Veteran's Day

-

20

10/12
Suicide Phage
ref list

21

10/14

Transposition

9
**
10/16
Sunday October 16th: LAST DAY TO DROP
**

-

10/17

Second Hourly Exam (Lectures 12-21)

-

22

10/19

Integrons, Mobile Cassettes, Pathogenicity Islands

9/ref list

23

10/21

Recombination

10

24

10/24

Recombination

10

25

10/26

Regulation: Lac Operon

12

26

10/28

Regulation: Trp Operon / Global Regulation: cAMP

12/13

27

10/31

Global Regulation: Quorum Sensing

13/ref

28

11/02

Global Regulation: Nitrogen Assimilation

13

29

11/04

Global Regulation: Heat Shock

13

30

11/07

Global Regulation rRNA/tRNA

13

31

11/09

Regulatory RNA -Riboswitches

12/ref

-

11/11

Veteran's Day

-

32

11/14

Regulatory RNA -sRNAs

13/ref

33

11/16

Overview of Reg. (Review for Ex 3)

12/13

-

11/18

Third Hourly Exam (Lectures 22-33)

-

34

11/21

Plasmid Addiction

4/ref

-

11/23

Thanksgiving Break

-

-

11/25

Thanksgiving Break

-

35

11/28

Programmed Cell Death

ref list

36

11/30

CRISPRs: Clustered Regularly Interspaced Short Palindromic Repeats

ref list

37

12/02

Reading the Text of the Bacterial Genome

ref list

38

12/05

Microarrays

13

39

12/07

Computers and Bioinformatics

notes

40

12/09

Final Review- CUMMULATIVE

-
***FINAL EXAM: Wednesday December 14th from 12:50 pm to 2:50 pm***

Please note that the dates scheduled for the three hourly exams are tentative; dates for the hourly
exams will be announced in class at least one week in advance. You will need to bring a calculator
to class on exam dates. The following lecture schedule is subject to change without notice.

REFERENCE LIST

PRACTICE EXAMS: See Blackboard
Questions and comments about MICR 460 to:
Comments and questions related to web server: webmaster@science.siu.edu

Last updated: August 9, 2011